Interleukin-1-receptor-associated kinase 2 (IRAK2)-mediated interleukin-1-dependent nuclear factor kappaB transactivation in Saos2 cells requires the Akt/protein kinase B kinase.

The post-receptor pathway that leads to nuclear factor kappaB (NF-kappaB) activation begins with the assembly of a membrane-proximal complex among the interleukin 1 (IL-1) receptors and the adaptor molecules, myeloid differentiation protein 88 (MyD88), IL-1-receptor-associated kinases (IRAKs) and tu...

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Main Authors: Cenni, Vittoria, Sirri, Alessandra, De Pol, Anto, Maraldi, Nadir Mario, Marmiroli, Sandra
Formato: Artigo
Idioma:Inglês
Publicado: 2003
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223745/
https://ncbi.nlm.nih.gov/pubmed/12906710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030028
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