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Inhibition of human ornithine decarboxylase activity by enantiomers of difluoromethylornithine.
Racemic difluoromethylornithine (D/L-DFMO) is an inhibitor of ODC (ornithine decarboxylase), the first enzyme in eukaryotic polyamine biosynthesis. D/L-DFMO is an effective anti-parasitic agent and inhibitor of mammalian cell growth and development. Purified human ODC-catalysed ornithine decarboxyla...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2003
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1223689/ https://ncbi.nlm.nih.gov/pubmed/12859253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030382 |
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