The conserved cis-Pro39 residue plays a crucial role in the proper positioning of the catalytic base Asp38 in ketosteroid isomerase from Comamonas testosteroni.

KSI (ketosteroid isomerase) from Comamonas testosteroni is a homodimeric enzyme that catalyses the allylic isomerization of Delta5-3-ketosteroids to their conjugated Delta4-isomers at a reaction rate equivalent to the diffusion-controlled limit. Based on the structural analysis of KSI at a high reso...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Nam, Gyu Hyun, Cha, Sun-Shin, Yun, Young Sung, Oh, Yun Hee, Hong, Bee Hak, Lee, Heung-Soo, Choi, Kwan Yong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2003
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223686/
https://ncbi.nlm.nih.gov/pubmed/12852789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030263
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