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Nitration of endogenous para-hydroxyphenylacetic acid and the metabolism of nitrotyrosine.
Reactive nitrogen species, such as peroxynitrite, can nitrate tyrosine in proteins to form nitrotyrosine. Nitrotyrosine is metabolized to 3-nitro-4-hydroxyphenylacetic acid (NHPA), which is excreted in the urine. This has led to the notion that measurement of urinary NHPA may provide a time-integrat...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2003
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1223612/ https://ncbi.nlm.nih.gov/pubmed/12797864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030670 |
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