Distinct regulation of cytosolic phospholipase A2 phosphorylation, translocation, proteolysis and activation by tumour necrosis factor-receptor subtypes.

The hormonally regulated Ca(2+)-dependent enzyme, cytosolic phospholipase A(2) (cPLA(2)) is activated by a range of inflammatory stimuli. Tumour necrosis factor-alpha (TNF) is one of the first known stimuli for cPLA(2) but it is not known whether both TNF receptor subtypes are involved in activating...

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Detalhes bibliográficos
Main Authors: Jupp, Orla J, Vandenabeele, Peter, MacEwan, David J
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223607/
https://ncbi.nlm.nih.gov/pubmed/12786601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030705
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