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Processing of alpha4 integrin by the proprotein convertases: histidine at position P6 regulates cleavage.

The proprotein convertases (PCs) participate in the limited proteolysis of integrin alpha4 subunit at the H(592)VISKR(597) downward arrow ST site (where underlined residues indicate positively charged amino acids important for PC-mediated cleavage and downward arrow indicates the cleavage site), sin...

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Autores principales: Bergeron, Eric, Basak, Ajoy, Decroly, Etienne, Seidah, Nabil G
Formato: Artigo
Lenguaje:Inglês
Publicado: 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223497/
https://ncbi.nlm.nih.gov/pubmed/12691605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021630
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