WASp verprolin homology, cofilin homology, and acidic region domain-mediated actin polymerization is required for T cell development

All members of the Wiskott–Aldrich syndrome protein (WASp) family contain a carboxyl-terminal verprolin homology, cofilin homology, and acidic region (VCA) domain that binds and activates the Arp2/3 complex, thereby linking these proteins to the induction of actin polymerization. Although the VCA do...

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Autori principali: Zhang, Jinyi, Shi, Fabio, Badour, Karen, Deng, Yupu, McGavin, Mary K. H., Siminovitch, Katherine A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2002
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC122349/
https://ncbi.nlm.nih.gov/pubmed/11842211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.042686099
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