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Regulation of the CDP-choline pathway by sterol regulatory element binding proteins involves transcriptional and post-transcriptional mechanisms.

The synthesis of phosphatidylcholine (PtdCho) by the CDP-choline pathway is under the control of the rate-limiting enzyme CTP:phosphocholine cytidylyltransferase (CCT). Sterol regulatory element binding proteins (SREBPs) have been proposed to regulate CCT at the transcriptional level, or via the syn...

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Detalhes bibliográficos
Main Authors: Ridgway, Neale D, Lagace, Thomas A
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223452/
https://ncbi.nlm.nih.gov/pubmed/12659631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20030252
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