Plasminogen activator inhibitor-1 polymers, induced by inactivating amphipathic organochemical ligands.

Negatively charged organochemical inactivators of the anti-proteolytic activity of plasminogen activator inhibitor-1 (PAI-1) convert it to inactive polymers. As investigated by native gel electrophoresis, the size of the PAI-1 polymers ranged from dimers to multimers of more than 20 units. As compar...

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Main Authors: Pedersen, Katrine E, Einholm, Anja P, Christensen, Anni, Schack, Lotte, Wind, Troels, Kenney, John M, Andreasen, Peter A
Formato: Artigo
Idioma:Inglês
Publicado: 2003
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223451/
https://ncbi.nlm.nih.gov/pubmed/12656676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021868
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