A peptide derived from α-fetoprotein prevents the growth of estrogen-dependent human breast cancers sensitive and resistant to tamoxifen

An 8-mer peptide (EMTOVNOG) derived from α-fetoprotein was compared with tamoxifen for activity against growth of human breast cancer xenografts implanted in immune-deficient mice. Both peptide and tamoxifen prevented growth of estrogen-receptor-positive MCF-7 and T47D human breast cancer xenografts...

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Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Bennett, James A., Mesfin, Fassil B., Andersen, Thomas T., Gierthy, John F., Jacobson, Herbert I.
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 2002
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122344/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11830647/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.251667098
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