טוען...
The soluble ectodomain of RetC634Y inhibits both the wild-type and the constitutively active Ret.
Substitution of Cys-634 in the extracellular domain of the Ret tyrosine kinase receptor causes its dimerization and activation of its transforming potential. To gain further insight into the molecular basis leading to Ret activation we purified a mutant protein consisting of the entire ectodomain of...
שמור ב:
| Main Authors: | , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2003
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1223439/ https://ncbi.nlm.nih.gov/pubmed/12630912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021530 |
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