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A Cross-Talk between TrkB and Ret Tyrosine Kinases Receptors Mediates Neuroblastoma Cells Differentiation

Understanding the interplay between intracellular signals initiated by multiple receptor tyrosine kinases (RTKs) to give the final cell phenotype is a major pharmacological challenge. Retinoic acid (RA)-treatment of neuroblastoma (NB) cells implicates activation of Ret and TrkB RTKs as critical step...

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Bibliografiske detaljer
Main Authors: Esposito, Carla Lucia, D'Alessio, Amelia, de Franciscis, Vittorio, Cerchia, Laura
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242850/
https://ncbi.nlm.nih.gov/pubmed/18286198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001643
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