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A Cross-Talk between TrkB and Ret Tyrosine Kinases Receptors Mediates Neuroblastoma Cells Differentiation

Understanding the interplay between intracellular signals initiated by multiple receptor tyrosine kinases (RTKs) to give the final cell phenotype is a major pharmacological challenge. Retinoic acid (RA)-treatment of neuroblastoma (NB) cells implicates activation of Ret and TrkB RTKs as critical step...

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Detalhes bibliográficos
Main Authors: Esposito, Carla Lucia, D'Alessio, Amelia, de Franciscis, Vittorio, Cerchia, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2242850/
https://ncbi.nlm.nih.gov/pubmed/18286198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001643
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