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Organization on the plasma membrane of the retinitis pigmentosa protein RP2: investigation of association with detergent-resistant membranes and polarized sorting.

Mutations in the retinitis pigmentosa protein gene RP2 account for up to 15% of X-linked retinitis pigmentosa. RP2 is a novel protein of unknown function, which is targeted to the plasma membrane by dual N-terminal acyl-modification. Dual-acylated proteins are targeted to lipid rafts, and some are s...

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Detalhes bibliográficos
Main Authors: Chapple, J Paul, Grayson, Celene, Hardcastle, Alison J, Bailey, Tracey A, Matter, Karl, Adamson, Peter, Graham, Catriona H, Willison, Keith R, Cheetham, Michael E
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223430/
https://ncbi.nlm.nih.gov/pubmed/12648035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021475
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