Synergism between nuclear receptors bound to specific hormone response elements of the hepatic control region-1 and the proximal apolipoprotein C-II promoter mediate apolipoprotein C-II gene regulation by bile acids and retinoids.

We have shown previously that the hepatic control region 1 (HCR-1) enhances the activity of the human apolipoprotein C-II (apoC-II) promoter in HepG2 cells via two hormone response elements (HREs) present in the apoC-II promoter. In the present paper, we report that the HCR-1 selectively mediates th...

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Bibliographic Details
Main Authors: Kardassis, Dimitris, Roussou, Anastasia, Papakosta, Paraskevi, Boulias, Konstantinos, Talianidis, Iannis, Zannis, Vassilis I
Format: Artigo
Language:Inglês
Published: 2003
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223391/
https://ncbi.nlm.nih.gov/pubmed/12585964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021532
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