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Increased expression of the lipocalin 24p3 as an apoptotic mechanism for MK886.
MK886, a strong proapoptotic agent, is an inhibitor of 5-lipoxygenase (LOX) through binding to the 5-LOX-activating protein (FLAP). Although MK886-induced apoptosis is through a FLAP-independent pathway, the precise mechanisms are not understood. In the present study, a possible role of 24p3, a lipo...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1223388/ https://ncbi.nlm.nih.gov/pubmed/12614196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021696 |
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