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Lipocalin-2 (24p3/Neutrophil Gelatinase-associated Lipocalin (NGAL)) Receptor Is Expressed in Distal Nephron and Mediates Protein Endocytosis

In the kidney, bulk reabsorption of filtered proteins occurs in the proximal tubule via receptor-mediated endocytosis (RME) through the multiligand receptor complex megalin-cubilin. Other mechanisms and nephron sites for RME of proteins are unclear. Recently, the secreted protein 24p3 (lipocalin-2,...

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Detalhes bibliográficos
Main Authors: Langelueddecke, Christian, Roussa, Eleni, Fenton, Robert A., Wolff, Natascha A., Lee, Wing-Kee, Thévenod, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249067/
https://ncbi.nlm.nih.gov/pubmed/22084236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.308296
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