Caenorhabditis elegans DNA mismatch repair gene msh-2 is required for microsatellite stability and maintenance of genome integrity

Mismatch repair genes are important in maintaining the fidelity of DNA replication. To determine the function of the Caenorhabditis elegans homologue of the MSH2 mismatch repair gene (msh-2), we isolated a strain of C. elegans with an insertion of the transposable element Tc1 within msh-2. Early-pas...

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Autors principals: Degtyareva, Natasha P., Greenwell, Patricia, Hofmann, E. Randal, Hengartner, Michael O., Zhang, Lijia, Culotti, Joseph G., Petes, Thomas D.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2002
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC122335/
https://ncbi.nlm.nih.gov/pubmed/11830642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.032671599
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