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Complement C1r and C1s genes are duplicated in the mouse: differential expression generates alternative isomorphs in the liver and in the male reproductive system.

C1r and C1s are the serine proteases that form the catalytic unit of the C1 complex, the first component of complement. In the present study, we found that the genes encoding murine C1r and C1s are duplicated. One set of these genes, referred to as c1rA and c1sA, are primarily expressed in the liver...

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Detalhes bibliográficos
Main Authors: Garnier, Gérard, Circolo, Antonella, Xu, Yuanyuan, Volanakis, John E
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223281/
https://ncbi.nlm.nih.gov/pubmed/12513694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021555
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