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Positive and negative regulation of T-cell activation through kinases and phosphatases.

The sequence of events in T-cell antigen receptor (TCR) signalling leading to T-cell activation involves regulation of a number of protein tyrosine kinases (PTKs) and the phosphorylation status of many of their substrates. Proximal signalling pathways involve PTKs of the Src, Syk, Csk and Tec famili...

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Detalhes bibliográficos
Main Authors: Mustelin, Tomas, Taskén, Kjetil
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223257/
https://ncbi.nlm.nih.gov/pubmed/12485116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021637
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