Early stimulation and late inhibition of peroxisome proliferator-activated receptor gamma (PPAR gamma) gene expression by transforming growth factor beta in human aortic smooth muscle cells: role of early growth-response factor-1 (Egr-1), activator protein 1 (AP1) and Smads.

Transforming growth factor beta (TGF beta) and peroxisome proliferator-activated receptor gamma (PPAR gamma) play major roles in the development of vascular diseases. It has been documented that PPAR gamma activation inhibits the TGF beta signal pathway in vascular smooth muscle cells (VSMC). Here w...

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Detalhes bibliográficos
Main Authors: Fu, Mingui, Zhang, Jifeng, Lin, Yimin, Zhu, Xiaojun, Zhao, Luning, Ahmad, Mushtaq, Ehrengruber, Markus U, Chen, Yuqing E
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223218/
https://ncbi.nlm.nih.gov/pubmed/12457461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021503
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