Specificity and robustness in transcription control networks

Recognition by transcription factors of the regulatory DNA elements upstream of genes is the fundamental step in controlling gene expression. How does the necessity to provide stability with respect to mutation constrain the organization of transcription control networks? We examine the mutation loa...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Sengupta, Anirvan M., Djordjevic, Marko, Shraiman, Boris I.
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 2002
Fag:	Biological Sciences
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122321/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11854503/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.022388499
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