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Specificity and robustness in transcription control networks

Recognition by transcription factors of the regulatory DNA elements upstream of genes is the fundamental step in controlling gene expression. How does the necessity to provide stability with respect to mutation constrain the organization of transcription control networks? We examine the mutation loa...

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Sonraí Bibleagrafaíochta
Main Authors: Sengupta, Anirvan M., Djordjevic, Marko, Shraiman, Boris I.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The National Academy of Sciences 2002
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC122321/
https://ncbi.nlm.nih.gov/pubmed/11854503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.022388499
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