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Specificity and robustness in transcription control networks

Recognition by transcription factors of the regulatory DNA elements upstream of genes is the fundamental step in controlling gene expression. How does the necessity to provide stability with respect to mutation constrain the organization of transcription control networks? We examine the mutation loa...

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書目詳細資料
Main Authors: Sengupta, Anirvan M., Djordjevic, Marko, Shraiman, Boris I.
格式: Artigo
語言:Inglês
出版: The National Academy of Sciences 2002
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC122321/
https://ncbi.nlm.nih.gov/pubmed/11854503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.022388499
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