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PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization.
cAMP is a second messenger that controls many key cellular functions. The only way to inactivate cAMP is to degrade it through the action of cAMP phosphodiesterases (PDEs). PDEs are thus poised to play a key regulatory role. PDE4 cAMP-specific phosphodiesterases appear to have specific functions wit...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2003
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1223165/ https://ncbi.nlm.nih.gov/pubmed/12444918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021698 |
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