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Interactions of the designed antimicrobial peptide MB21 and truncated dermaseptin S3 with lipid bilayers: molecular-dynamics simulations.

Molecular-dynamics simulations covering 30 ns of both a natural and a synthetic antimicrobial peptide in the presence of a zwitterionic lipid bilayer were performed. In both simulations, copies of the peptides were placed in an alpha-helical conformation on either side of the bilayer about 10 A (1 A...

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Detalhes bibliográficos
Main Authors: Shepherd, Craig M, Vogel, Hans J, Tieleman, D Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223151/
https://ncbi.nlm.nih.gov/pubmed/12423203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021255
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