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Mutagenesis of a functional chimeric gene in yeast identifies mutations in the simian virus 40 large T antigen J domain

Simian virus 40 large T antigen contains an amino terminal J domain that catalyzes T antigen-mediated viral DNA replication and cellular transformation. To dissect the role of the J domain in these processes, we exploited the genetic tools available only in the yeast Saccharomyces cerevisiae to isol...

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Autors principals: Fewell, Sheara W., Pipas, James M., Brodsky, Jeffrey L.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC122309/
https://ncbi.nlm.nih.gov/pubmed/11854498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.042670999
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