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Mutagenesis of a functional chimeric gene in yeast identifies mutations in the simian virus 40 large T antigen J domain
Simian virus 40 large T antigen contains an amino terminal J domain that catalyzes T antigen-mediated viral DNA replication and cellular transformation. To dissect the role of the J domain in these processes, we exploited the genetic tools available only in the yeast Saccharomyces cerevisiae to isol...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The National Academy of Sciences
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122309/ https://ncbi.nlm.nih.gov/pubmed/11854498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.042670999 |
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