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Insulin stimulation of pyruvate dehydrogenase in adipocytes involves two distinct signalling pathways.
In isolated rat adipocytes, the insulin stimulation of pyruvate dehydrogenase can be partially inhibited by inhibitors of PI3K (phosphoinositide 3-kinase) and MEK1/2 (mitogen-activated protein kinase/extracellular signal-regulated kinase kinase). In combination, U0126 and wortmannin completely block...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1223089/ https://ncbi.nlm.nih.gov/pubmed/12374570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020920 |
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