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Functional studies on the role of the C-terminal domain of mammalian polo-like kinase

Mammalian polo-like kinase (Plk) acts at various stages in early and late mitosis. Plk is phosphorylated and activated in mitosis, and the proper subcellular localization of Plk is essential for mitotic regulation. We have observed that overexpression of the C-terminal domain of Plk is more effectiv...

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Detalhes bibliográficos
Main Authors: Jang, Young-Joo, Lin, Chin-Yo, Ma, Sheng, Erikson, Raymond L.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC122306/
https://ncbi.nlm.nih.gov/pubmed/11854496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.042689299
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