Inhibition of autophagic proteolysis by inhibitors of phosphoinositide 3-kinase can interfere with the regulation of glycogen synthesis in isolated hepatocytes.

Amino acid-induced cell swelling stimulates conversion of glucose into glycogen in isolated hepatocytes. Activation of glycogen synthase (GS) phosphatase, caused by the fall in intracellular chloride accompanying regulatory volume decrease, and activation of phosphoinositide 3-kinase (PI 3-kinase),...

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Detalhes bibliográficos
Main Authors: Dubbelhuis, Peter F, Van Sluijters, Daphne A, Blommaart, Edward F C, Gustafson, Lori A, Van Woerkom, George M, Herling, Andreas W, Burger, Hans-Joerg, Meijer, Alfred J
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223050/
https://ncbi.nlm.nih.gov/pubmed/12371905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021340
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