Comparative characterization of hexose transporters of Plasmodium knowlesi, Plasmodium yoelii and Toxoplasma gondii highlights functional differences within the apicomplexan family.

Chemotherapy of apicomplexan parasites is limited by emerging drug resistance or lack of novel targets. PfHT1, the Plasmodium falciparum hexose transporter 1, is a promising new drug target because asexual-stage malarial parasites depend wholly on glucose for energy. We have performed a comparative...

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Main Authors: Joët, Thierry, Holterman, Lennart, Stedman, Timothy T, Kocken, Clemens H M, Van Der Wel, Annemarie, Thomas, Alan W, Krishna, Sanjeev
Format: Artigo
Jezik:Inglês
Izdano: 2002
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1223042/
https://ncbi.nlm.nih.gov/pubmed/12238947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20021189
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