Mitochondrial aspartate aminotransferase catalyses cysteine S-conjugate beta-lyase reactions.

Rat liver mitochondrial aspartate aminotransferase (a homodimer) was shown to catalyse a beta-lyase reaction with three nephrotoxic halogenated cysteine S-conjugates [ S -(1,1,2,2-tetrafluoroethyl)-L-cysteine, S -(1,2-dichlorovinyl)-L-cysteine and S -(2-chloro-1,1,2-trifluoroethyl)-L-cysteine], and...

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Autori principali: Cooper, Arthur J L, Bruschi, Sam A, Iriarte, Ana, Martinez-Carrion, Marino
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2002
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222959/
https://ncbi.nlm.nih.gov/pubmed/12137566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020531
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