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Mechanism by which metal cofactors control substrate specificity in pyrophosphatase.

Family I soluble pyrophosphatases (PPases) exhibit appreciable ATPase activity in the presence of a number of transition metal ions, but not the physiological cofactor Mg(2+). The results of the present study reveal a strong correlation between the catalytic efficiency of three family I PPases (from...

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Detalhes bibliográficos
Main Authors: Zyryanov, Anton B, Shestakov, Alexander S, Lahti, Reijo, Baykov, Alexander A
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222946/
https://ncbi.nlm.nih.gov/pubmed/12169093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020880
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