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Cystathionine β-Synthase (CBS) Domains Confer Multiple Forms of Mg(2+)-dependent Cooperativity to Family II Pyrophosphatases
Regulated family II pyrophosphatases (CBS-PPases) contain a nucleotide-binding insert comprising a pair of cystathionine β-synthase (CBS) domains, termed a Bateman module. By binding with high affinity to the CBS domains, AMP and ADP usually inhibit the enzyme, whereas ATP activates it. Here, we dem...
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| Päätekijät: | , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society for Biochemistry and Molecular Biology
2014
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4132789/ https://ncbi.nlm.nih.gov/pubmed/24986864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.589473 |
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