Growth inhibition by the muscarinic M(3) acetylcholine receptor: evidence for p21(Cip1/Waf1) involvement in G(1) arrest.

We have assessed the growth response of Chinese-hamster ovary (CHO) cells to activation of recombinantly expressed G-protein-coupled muscarinic M(2) or M(3) acetylcholine receptors (AChRs). We show that activation of these receptors leads to divergent growth responses: M(2) AChR activation causes an...

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Bibliografiske detaljer
Main Authors: Burdon, Drew, Patel, Rajnikant, Challiss, R A John, Blank, Jonathan L
Format: Artigo
Sprog:Inglês
Udgivet: 2002
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222904/
https://ncbi.nlm.nih.gov/pubmed/12126481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020446
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