Organization of the multifunctional enzyme type 1: interaction between N- and C-terminal domains is required for the hydratase-1/isomerase activity.

Rat peroxisomal multifunctional enzyme type 1 (perMFE-1) is a monomeric protein of beta-oxidation. We have defined five functional domains (A, B, C, D and E) in the perMFE-1 based on comparison of the amino acid sequence with homologous proteins from databases and structural data of the hydratase-1/...

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Autors principals: Kiema, Tiila-Riikka, Taskinen, Jukka P, Pirilä, Päivi L, Koivuranta, Kari T, Wierenga, Rik K, Hiltunen, J Kalervo
Format: Artigo
Idioma:Inglês
Publicat: 2002
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222896/
https://ncbi.nlm.nih.gov/pubmed/12106015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020292
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