Structural enzymology comparisons of multifunctional enzyme, type‐1 (MFE1): the flexibility of its dehydrogenase part

Multifunctional enzyme, type‐1 (MFE1) is a monomeric enzyme with a 2E‐enoyl‐CoA hydratase and a 3S‐hydroxyacyl‐CoA dehydrogenase (HAD) active site. Enzyme kinetic data of rat peroxisomal MFE1 show that the catalytic efficiencies for converting the short‐chain substrate 2E‐butenoyl‐CoA into acetoacet...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Kasaragod, Prasad, Midekessa, Getnet B., Sridhar, Shruthi, Schmitz, Werner, Kiema, Tiila‐Riikka, Hiltunen, Jukka K., Wierenga, Rik K.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5715344/
https://ncbi.nlm.nih.gov/pubmed/29226071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12337
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