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A poxvirus-like type IB topoisomerase family in bacteria

We report that diverse species of bacteria encode a type IB DNA topoisomerase that resembles vaccinia virus topoisomerase. Deinococcus radiodurans topoisomerase IB (DraTopIB), an exemplary member of this family, relaxes supercoiled DNA in the absence of a divalent cation or ATP. DraTopIB has a compa...

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Autors principals: Krogh, Berit Olsen, Shuman, Stewart
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC122283/
https://ncbi.nlm.nih.gov/pubmed/11830640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.032613199
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