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A method for detection of overoxidation of cysteines: peroxiredoxins are oxidized in vivo at the active-site cysteine during oxidative stress.

Peroxiredoxins are often encountered as double spots when analysed by two-dimensional electrophoresis. The quantitative balance between these two spots depends on the physiological conditions, and is altered in favour of the acidic variant by oxidative stress for all the peroxiredoxins we could anal...

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Détails bibliographiques
Auteurs principaux: Wagner, Elsa, Luche, Sylvie, Penna, Lucia, Chevallet, Mireille, Van Dorsselaer, Alain, Leize-Wagner, Emmanuelle, Rabilloud, Thierry
Format: Artigo
Langue:Inglês
Publié: 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222825/
https://ncbi.nlm.nih.gov/pubmed/12059788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020525
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