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A novel form of the RelA nuclear factor kappaB subunit is induced by and forms a complex with the proto-oncogene c-Myc.

Members of both Myc and nuclear factor kappaB (NF-kappaB) families of transcription factors are found overexpressed or inappropriately activated in many forms of human cancer. Furthermore, NF-kappaB can induce c-Myc gene expression, suggesting that the activities of these factors are functionally li...

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Main Authors: Chapman, Neil R, Webster, Gill A, Gillespie, Peter J, Wilson, Brian J, Crouch, Dorothy H, Perkins, Neil D
Format: Artigo
Jezik:Inglês
Izdano: 2002
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222795/
https://ncbi.nlm.nih.gov/pubmed/12027803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20020444
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