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Total direct chemical synthesis and biological activities of human group IIA secretory phospholipase A2.

Human group IIA secretory phospholipase A(2) (hGIIA sPLA(2)) is reported to be involved in inflammation, since its expression level is enhanced under various inflammatory conditions. In this work, we report the total chemical synthesis of this enzyme (124 amino acids) by solid-phase method. The iden...

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Detalhes bibliográficos
Main Authors: Dong, Chang-Zhi, Romieu, Anthony, Mounier, Carine M, Heymans, Françoise, Roques, Bernard P, Godfroid, Jean-Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222685/
https://ncbi.nlm.nih.gov/pubmed/11936952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20011648
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