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Characterization of recombinant glutathionylspermidine synthetase/amidase from Crithidia fasciculata.

Trypanothione [N1,N8-bis(glutathionyl)spermidine] is a unique metabolite found only in trypanosomatids, where it subsumes many of the functions of GSH in other organisms. In Crithidia fasciculata, two distinct ATP-dependent ligases, glutathionylspermidine synthetase (GspS; EC 6.3.1.8) and trypanothi...

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Detalhes bibliográficos
Main Authors: Oza, Sandra L, Ariyanayagam, Mark R, Fairlamb, Alan H
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222616/
https://ncbi.nlm.nih.gov/pubmed/12049631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20011370
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