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Adenovirus-directed expression of Q227L-Gα(s) inhibits growth of established tumors of later-stage human breast cancer cells in athymic mice

Elevation of cAMP inhibits proliferation and expression of the transformed phenotype in several cell types. We studied the effects of elevation of cAMP and expression of mutant (Q227L) activated Gα(s) on the proliferation and tumorigenic capability of the later stage, metastatic estrogen-independent...

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Bibliografske podrobnosti
Main Authors: Santore, Tara Ann, Chen, Yibang, Smit, Martine J., Iyengar, Ravi
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2002
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC122249/
https://ncbi.nlm.nih.gov/pubmed/11805301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.032661999
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