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Adenovirus-directed expression of Q227L-Gα(s) inhibits growth of established tumors of later-stage human breast cancer cells in athymic mice
Elevation of cAMP inhibits proliferation and expression of the transformed phenotype in several cell types. We studied the effects of elevation of cAMP and expression of mutant (Q227L) activated Gα(s) on the proliferation and tumorigenic capability of the later stage, metastatic estrogen-independent...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The National Academy of Sciences
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122249/ https://ncbi.nlm.nih.gov/pubmed/11805301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.032661999 |
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