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Involvement of protein kinase D in Fc gamma-receptor activation of the NADPH oxidase in neutrophils.

Protein kinases involved in the activation of the NADPH oxidase by Fc gamma receptors in neutrophils were studied. Of three different protein kinase C (PKC) inhibitors, Gö 6976 inhibited the NADPH oxidase completely, whereas bisindolylmaleimide I and Ro 31-8220 caused a 70-80% inhibition. Thus a Gö...

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Detalles Bibliográficos
Main Authors: Davidson-Moncada, Jan K, Lopez-Lluch, Guillermo, Segal, Anthony W, Dekker, Lodewijk V
Formato: Artigo
Idioma:Inglês
Publicado: 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222456/
https://ncbi.nlm.nih.gov/pubmed/11903052
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