Monitoring of exocytosis and endocytosis of insulin secretory granules in the pancreatic beta-cell line MIN6 using pH-sensitive green fluorescent protein (pHluorin) and confocal laser microscopy.

The dynamics of exocytosis/endocytosis of insulin secretory granules in pancreatic beta-cells remains to be clarified. In the present study, we visualized and analysed the motion of insulin secretory granules in MIN6 cells using pH-sensitive green fluorescent protein (pHluorin) fused to either insul...

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Autores principales: Ohara-Imaizumi, Mica, Nakamichi, Yoko, Tanaka, Toshiaki, Katsuta, Hidenori, Ishida, Hitoshi, Nagamatsu, Shinya
Formato: Artigo
Lenguaje:Inglês
Publicado: 2002
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222453/
https://ncbi.nlm.nih.gov/pubmed/11903049
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