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Ceramides increase the activity of the secretory phospholipase A2 and alter its fatty acid specificity.

Modulation of human recombinant secretory type II phospholipase A(2) activity by ceramide and cholesterol was investigated using model glycerophospholipid substrates composed of phosphatidylethanolamine and phosphatidylserine dispersed in aqueous medium. Enzyme activity was monitored by measurement...

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Detalhes bibliográficos
Main Authors: Koumanov, Kamen S, Momchilova, Albena B, Quinn, Peter J, Wolf, Claude
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222449/
https://ncbi.nlm.nih.gov/pubmed/11903045
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