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Regulation of the activity and fatty acid specificity of lecithin-cholesterol acyltransferase by sphingomyelin, and its metabolites ceramide and ceramide phosphate

Sphingomyelin (SM), the second most abundant phospholipid in plasma lipoproteins, was previously shown to be a physiological inhibitor of the lecithin-cholesterol acyltransferase (LCAT) reaction. In this study, we investigated the effects of its metabolites, ceramide and ceramide phosphate, on the a...

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Main Authors: Subbaiah, Papasani V., Horvath, Peter, Achar, Srinivasa B.
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1451158/
https://ncbi.nlm.nih.gov/pubmed/16605271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0600704
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