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Cyclophilin-A is involved in excitotoxin-induced caspase activation in rat neuronal B50 cells.

Glutamate and the NO donor, nitroprusside, synergistically induced the death of B50 cells from a rat CNS-derived neuroblastoma cell line. With low [nitroprusside] (10 microM) both nitroprusside and glutamate were required. Under these conditions, nuclei became pyknotic and caspases were activated. T...

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Detalhes bibliográficos
Main Authors: Capano, Michela, Virji, Sukaina, Crompton, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222447/
https://ncbi.nlm.nih.gov/pubmed/11903043
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