Lipid deprivation increases surfactant phosphatidylcholine synthesis via a sterol-sensitive regulatory element within the CTP:phosphocholine cytidylyltransferase promoter.

Lipid-deprived mice increase alveolar surfactant disaturated phosphatidylcholine (DSPtdCho) synthesis compared with mice fed a standard diet by increasing expression of CTP:phosphocholine cytidylyltransferase (CCT), the rate-limiting enzyme for DSPtdCho synthesis. We previously observed that lipid d...

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Detalhes bibliográficos
Main Authors: Mallampalli, Rama K, Ryan, Alan J, Carroll, James L, Osborne, Timothy F, Thomas, Christie P
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222362/
https://ncbi.nlm.nih.gov/pubmed/11829742
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