Phosphatidylcholine Synthesis for Lipid Droplet Expansion Is Mediated by Localized Activation of CTP:Phosphocholine Cytidylyltransferase

Lipid droplets (LDs) are cellular storage organelles for neutral lipids that vary in size and abundance according to cellular needs. Physiological conditions that promote lipid storage rapidly and markedly increase LD volume and surface. How the need for surface phospholipids is sensed and balanced...

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Main Authors: Krahmer, Natalie, Guo, Yi, Wilfling, Florian, Hilger, Maximiliane, Lingrell, Susanne, Heger, Klaus, Newman, Heather W., Schmidt-Supprian, Marc, Vance, Dennis E., Mann, Matthias, Farese, Robert V., Walther, Tobias C.
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735358/
https://ncbi.nlm.nih.gov/pubmed/21982710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2011.07.013
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